Procedural Dermatology » Autologous growth factor
factor treatment or Platelet Rich
Plasma (PRP) Therapy
The History of
PRP first began being
researched in the 1970s. It was first used in an open heart surgery procedure
in Italy in 1987.
After successfully being used
in that procedure, PRP grew in popularity starting in the mid-1990s. Today,
Platelet rich plasma treatment has been applied to a variety of medical fields,
including cosmetic surgery, dentistry, sports medicine, and pain management in
many clinics around the world.
Plasma (PRP) is premium
anti-aging skin treatment.
The treatment uses components called platelets
contained in the patient's own blood.
Platelets contain an abundance of growth factors
which stimulate stem cell production, collagen synthesis, proliferation of
fibroblasts and angiogenesis to rejuvenate the skin.
PRP therapy has the effect of potentiating your
innate natural healing power and tissue reorganization potential.
Platelet Growth Factor
Stimulates Stem Cell Production
PRP (Platelet rich plasma) is
defined as autologous blood with a concentration of platelets above baseline
• Average normal platelet count
= 200,000/ul (normal range: 150,000 – 350,000/ul)
• PRP count= 1,000,000/ul (5x concentration)
Blood is made up of 4
components including plasma, red blood cell (RBC), white blood cell (WBC), and
A normal blood would be made up of 93% red blood cell, 6%
platelets and 1% white blood cell. Through the use of centrifuge, the blood
components are separated and the ratios are changed in PRP to 94% platelets
5% red blood cell.
Growth Factor Function
Growth Factor is a
naturally occurring substance capable of stimulating cellular growth,
proliferation, healing, and cellular differentiation.
Usually it is a protein or a steroid hormone.
Growth factors are important
for regulating a variety of cellular processes and typically act as signaling
molecules between cells. They often promote cell differentiation and
maturation, which varies between growth factors.
Examples of some Growth Factors
- Transforming Growth Factor-beta
- Platelet Derived Growth Factor
- Epidermal Growth Factor (EGF)
- Vascular Endothelial Growth
- Basic Fibroblast Growth Factor
- Connective Tissue Growth Factor
PRP injection procedure
Step 1: Blood is drawn from the
patient 15-20 CC
Step 2: The collected blood is
placed in a centrifuge that concentrates the platelets and growth factors into
a smaller amount of plasma.
Step 3: The Platelet-Rich Plasma is then carefully injected into the site
around your injured tendon.
PRP Therapy Advantages
• No risk of transmissible
infection and allergic reaction
• Natural result
• Longer duration of efficacy
• No need for skin incision
• Simple procedure
• Minimal discomfort
• Shorten downtime
Depending on the severity of
skin troubles, most patients require between one and three treatments. Each set
of treatment is spaced 3 to 4 weeks apart.
- Avoid corticosteroid medications for 2 to 3 weeks prior to the procedure
- Stop taking non-steroidal anti-inflammatory drugs (NSAIDs), such
as aspirin or ibuprofen, or arthritis medications such as Celebrex, a week
prior to the procedur
- Do not take anticoagulation medication for 5 days
before the procedure
- Drink plenty of fluids the day before the procedur
- Some patients may require anti-anxiety medication immediately
before the procedure
- You may experience some discomfort, but do not despair! Your body
is reacting in the normal and desired way
to the sudden influx of platelets and healing factors.
- You may want to ice and elevate your injury, perhaps even use
Tylenol for pain relief. But ibuprofen, Advil and other NSAIDs will produce the
opposite reaction that the procedure is trying to create.
- This treatment should be just a part of a rehabilitation planned
by your doctors in order to get you back to your best. Finally, the PRP injection process may seem to be over-simplified, but it really is a very easy
and effective way to treat tendonitis in all its forms.
Who cannot have PRP treatment?
- People who are suffering from skin diseases
such as SLE, allergies, porphyria, cancer, severe metabolic and systematic
disorders, abnormal platelet function, critical thomobocytopemia, haemodynamic
instability, anti coagulation therapy and, underlying sepsis.
- Patients with severe anemia, low platelet
count, abnormal platelet function, active systemic infection or those with an
PRP Injection for Facial
PRP stimulates your own
collagen to grow for total facial rejuvenation rather than individual wrinkle
PRP is used for:-
-Volumizing faces that are
beginning to look drawn
-Plumping out cheek indentations
and soften under eye hollows
-Improving the skin tone,
tightness, and texture
-Filling in areas where
hyaluronic acid fillers cannot reach or are not safe to use.
Benefits of PRP Injection for
It can improve skin tone and
texture, tighten skin, soften lines and pores.
Results begin to show 3-4 weeks
after the treatment session and continue to improve with time. Three treatment
sessions are generally recommended, spaced 1-2 months apart, to achieve the
How many treatments of PRP Injection for Facial
Rejuvenation are required?
The initial treatment for PRP
is one treatment a month for 3 to 4 months, then repeat treatments either
6-monthly or 12-monthly, depending on your skin and results.
PRP therapy can be combined
with laser treatments, microdermabrasion, chemical peels, botox or derma filler
for the best results.
When will be able to see the
result after PRP Injection for Facial
Results become visible at 3
weeks and increase gradually over ensuing months with improvement in the skin’s
texture and tone.
PRP Injection for Hair Loss
PRP contains growth factors
that help to repair the injury and damaged caused by DHT hormones to your hair
follicles, therefore helping to promote the regrowth of thicker and healthier
PRP will signal the body to
send PLATELETS and PLASMA to the area, to repair the injured cells. Adding
additional PRP increases the amount of repairing cells (platelets) and
nutrients (plasma) in the hair loss region. This exposes the skin cells and the
hair follicles to large amounts of healing platelets and nutrient rich plasma.
Benefits of PRP Injection for Hair
PREVENT & slow down the
rate of hair loss, thinning, hair shedding & hair fall.
REGROW thinning hair thicker,
fuller and healthier.
BOOST the health &
condition of the scalp naturally
ACTIVATE the regrowth of
dormant hair follicles by encouraging the growth phase of your hair (anagen
HAIR TRANSPLANT PRP has shown
to help prepare the area for a hair transplant + also to assist with the
recovery and growth rate after receiving a hair transplant.
How many treatments of PRP Injection for Hair Loss are
We recommend continuously 4 times
treatments, spaced up to 4 weeks apart. Then it can be continue to enhance the
result. Patients are recommended to receive a treatment every 1-3 months apart.
PRP therapy can be combined
with laser treatments, hair growth lotion and pills for the best results.
When will the hairs be
regenerated after PRP Injection for Hair Loss?
It will be within 1 or 2 months
after the treatment.
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